Novo Nordisk announced that CEO Lars Fruergaard Jørgensen will step down in response to growing market pressures and a sharp decline in the company’s share price. The decision was made jointly by Jørgensen, the company board, and the Novo Nordisk Foundation. The announcement cited recent market challenges, the falling stock value, and the foundation’s wishes as key drivers behind the leadership transition. Jørgensen will remain in his role temporarily to ensure a smooth handover while the company searches for his successor.
Jørgensen Praised for Growth Amid Falling Shares and Fierce Weight-Loss Drug Competition
Despite the recent turbulence, Jørgensen is being lauded for his contributions over the past eight years. During his tenure, Novo Nordisk saw a substantial increase in sales, profits, and share price, nearly tripling in value before the downturn began in 2024. His leadership helped position the company as a major force in diabetes and obesity care, with significant investments in innovative treatments and chronic disease management. The company acknowledged his pivotal role in transforming Novo Nordisk into a global pharmaceutical leader.

The recent 50% drop in Novo Nordisk’s share price has been a major concern, erasing more than $300 billion in market value. This sharp decline is attributed in part to intensifying competition in the weight-loss drug market, especially from U.S.-based pharmaceutical giant Eli Lilly. Both companies are vying for dominance in the fast-growing obesity drug market. Safety concerns around these medications, raised by medical professionals, have also cast a shadow over the industry, further impacting investor confidence.
Intensifying Drug Competition Amid Leadership Shift and Soaring Obesity Market Projections
The market for weight-loss drugs is projected to skyrocket in the coming years, with Morgan Stanley estimating it could grow to between $105 billion and $144 billion by 2030. Novo Nordisk’s Wegovy was the first drug approved to help patients lose over 10% of body weight, marking a breakthrough in obesity treatment. However, Eli Lilly has since introduced Zepbound, a rival drug that shows even greater weight-loss results, intensifying competition. Novo Nordisk’s Ozempic and Eli Lilly’s Mounjaro also compete in the diabetes treatment space.
As Novo Nordisk prepares for a leadership transition, the company is working through a period of rapid change and heightened competition in the pharmaceutical industry. Jørgensen will remain in his role to help ensure a smooth handover as the search for his successor continues. Meanwhile, Lars Rebien Sorensen, chair of the Novo Nordisk Foundation, will be joining the company’s board.
Despite recent challenges, Novo Nordisk remains dedicated to advancing treatments for diabetes, obesity, and other serious chronic conditions, with a focus on rebuilding momentum and restoring investor confidence under new leadership.